Viruses, Other Pathogenic Microorganisms and Esophageal Cancer

Viruses, Other Pathogenic Microorganisms and Esophageal Cancer.

BACKGROUND Esophageal cancer (EC) is the eighth most prevalent malignant tumor and the sixth leading cause of cancer mortality throughout the world. Despite the technical developments in diagnosis and treatment, the 5-year survival rate is still low. The etiology of EC remains poorly understood; multiple risk factors may be involved and account for the great variation in EC incidence in differe...

> Pathogenic Microorganisms and Viruses in Groundwater

Pathogenic Microorganisms and Pancreatic Cancer.

BACKGROUND Pancreatic cancer is one of the most lethal cancers worldwide. No effective screening methods exist, and available treatment modalities do not effectively treat the disease. Established risk factors for pancreatic cancer, including smoking, chronic pancreatitis, obesity and type 2 diabetes mellitus, collectively account for less than half of all pancreatic cancer cases. Accumulating ...

Contamination of polio vaccines by monkey viruses and other microorganisms

Polio viruses for the production of polio vaccines have been cultured on monkey kidney tissue and cell lines. These are naturally infected by monkey (simian) viruses and other microorganisms and agents (protozoans, amoebas). They cause, and/or are a co-factor, in a great variety of cancers and other diseases. The methods used to “clean-up” the animal tissue and/or microorganisms of these undesi...

ZMPSTE24 defends against influenza and other pathogenic viruses

Zinc metallopeptidase STE24 (ZMPSTE24) is a transmembrane metalloprotease whose catalytic activity is critical for processing lamin A on the inner nuclear membrane and clearing clogged translocons on the endoplasmic reticulum. We now report ZMPSTE24 is a virus-specific effector that restricts enveloped RNA and DNA viruses, including influenza A, Zika, Ebola, Sindbis, vesicular stomatitis, cowpo...